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Clinical utility of serologic testing for celiac disease in Ontario

10 Dec 2010

The mandate of the Medical Advisory Secretariat is to provide evidence-based policy advice on the coordinated uptake of health services and new health technologies in Ontario to the Ministry of Health and Long-Term Care and to the healthcare system. [...] First degree relatives of patients with celiac disease: 2 to 20% Prevalence of Celiac Disease in Subjects with Symptoms Consistent with the Disease The prevalence of celiac disease in subjects with symptoms consistent with the disease varied widely among studies, i.e., 1.5% to 50% in adult studies, and 1.1% to 17% in pediatric studies. [...] The literature indicates that the diagnostic accuracy of serologic tests for celiac disease may be affected in patients with chronic liver disease, therefore, the studies identified through the systematic literature review that evaluated the diagnostic accuracy of serologic tests for celiac disease in patients with chronic liver disease were summarized. [...] Clinical Utility of Serologic Testing for Celiac Disease – OHTAS, 2010; 10(21) 13 Clinical Validity and Clinical Utility of Serologic Testing in the Diagnosis of Celiac Disease The clinical validity of serologic tests in the diagnosis of celiac disease was considered high in subjects with symptoms consistent with this disease due to. [...] The panel of tests is the commonly used strategy in the province of Ontario therefore the impact to the system would be $13.6M, $14.5M and $15.3M respectively in the next three years based on past volumes and trends in the province and basecase expected costs.
health science and technology research systematic reviews biology diet medical research medicine medical diagnosis serologic tests evidence-based medicine sensitivity and specificity diagnostic celiac disease clinical medicine evidence-based healthcare policy health treatment health sciences government health care sensitivity likelihood ratios in diagnostic testing gluten-free diet coeliac disease gliadin dermatitis herpetiformis anti-gliadin antibody anti-gliadin antibodies anti-transglutaminase antibodies
ISBN
9781443532242
Pages
111
Published in
Canada

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