This paper investigates the net present value of the investment in the five year comprehensive program proposed in the Report to the Minister of Health (Ashley et al., 1999) and the report of the Ontario Tobacco Strategy Steering Committee (2002). [...] The Report to the Minister of Health from Her Expert Panel on the Renewal of the Ontario Tobacco Strategy (Ashley et al., 1999; herein Report to the Minister of Health) outlines the elements of a successful program for Ontario. [...] This paper investigates the net present value of the investment in the program proposed in the Report to the Minister of Health and OTSSC (2002). [...] Section IV provides an overview of the approach we use to calculate the net benefit to the Ontario government of implementing the program and details the costs of the program. [...] The OTSSC (2002) and the Report to the Minister of Health (1999) provide recent and relevant examinations of the evidence base for the measures in the program.