The various products differ in the speed of onset, the duration of effects and the extent of specific effects. [...] With repeated use, tolerance to sedative medications begins to develop, which causes a reduction in the extent of effects and requires an increase in dose to maintain the desired effect. [...] Other effects of sedatives are similar to those of alcohol, producing a state of intoxication that includes impaired motor coordination and judgment, slurred speech, and lowered inhibitions. [...] The ability of sedatives to produce feelings of relaxation and intoxication is the reason for their non-medical use. [...] When used over long periods of time, tolerance to some of the impairing effects of sedatives can develop.