This document provides the results of a research program that has spanned a decade and has provided important information and unique insights into the quality of life and well-being of the citizens of Saskatoon. The current report is organized into three main sections. Section 1 describes the research methodology, data collection, and analysis. In Section 2, the results of a detailed analysis of the results of the Quality of Life telephone survey over the 2001-2004-2007-2010 study period. Section 3 summarizes the results of the face-to-face interviews conducted as a follow-up to the telephone survey. Section 4 provides a summary of the focus group results. Finally, Section 5 discusses key trends of a decade of Quality of Life research in Saskatoon.