Detailed summary information is presented in Tables 2 and 3. Five of the included studies provided evidence that MST was effective in improving outcomes for children and youth with psychiatric and behavioural issues compared to 1-2,4-6 treatment as usual (TAU). [...] The RCT that examined the effect of MST versus TAU for reducing out of home placement in children with moderate to severe 3 antisocial behaviour resulted in no difference between the two groups. [...] The National Institute for Health and Care Excellence guidelines recommend the use of 7 MST for young people with problematic sexual behaviour. [...] The American Academy of Child and Adolescent Psychiatry identified MST as a community-based therapy option with racial and ethnic specific 9 evidence for conduct disturbances, substance abuse, and suicidality. [...] TAU disorder, conduct disorder, and treatment N = 256 property offences in the MST group MST not more effective than TAU at reducing violence Ethnicity and age were not moderators on the effectiveness of MST Sex was a moderator; MST had a larger positive effect on cognition for boys than for girls SUMMARY OF ABSTRACTS Multisy stemic Therapy.