Clearing the Air: A systematic review on the harms and benefits of e-cigarettes and Renée O’Leary, PhD(c) vapour devices Marjorie MacDonald, PhD, RN. [...] Clearing the Air: A systematic review on the harms and benefits of e-cigarettes and vapour devices. [...] The overriding caveat for evaluating the findings is that the plethora of different devices and liquids means that the findings of a particular study may not be generalizable to other devices. [...] The research is mixed as to whether vapour device use had an effect on the desire or ability of those who smoke to quit tobacco use, but based on the preponderance of findings, it is clear that claims for a negative impact on cessation are unjustified. [...] A key issue around vapour devices is the concern that youth use of vapour devices could lead to their uptake of tobacco products.