Post-marketing pharmacosurveillance in Canada : Pharmacovigilance après la commercialisation au Canada

Choosing the appropriate pharmacosurveillance strategy depends on the nature of the research questions, the health care system context, the availability of data sources, the required time line for results, and the availability of research expertise. [...] Measures Used to Determine Success/Failure • The number of AEs for which a causal relationship between the drug and the AE is assessed and established. [...] Paediatric suspected ADRs reported to the CADRMP Goals The goals/objectives of this research are to: • catalogue all paediatric suspected ADRs reported to the CADRMP at Health Canada from January 1, 1998, to May 30, 2002; • identify the drugs most frequently reported; • identify the types of reactions reported; and • identify the demographic characteristics of the children for whom ADR reports hav [...] Goal setting The project is funded by Genome Canada, Genome British Columbia, the UBC Faculties of Pharmaceutical Sciences and Medicine, the Child and Family Research Institute (BC), the Canadian Genetic Diseases Network, the Canada Gene Cure Foundation, the University of Western Ontario, Illumina, IBM, and the Canadian Society for Clinical Pharmacology. [...] The key objectives of the project were: (1) to work with formulary decision-makers in Ontario and BC to identify pharm acosurveillance information needs, (2) to develop and refine techniques for producing evidence and to share those techniques with research teams in both provinces; and (3) to assess the impact of pharmacosurveillance on decision-making.