Guaiac fecal occult blood test (FOBT) laboratory standards / : EBS 15-4

"Questions: 1. Guaiac Fecal Occult Blood Test (gFOBT) performance factors: What are the performance characteristics (sensitivity, specificity, positivity, and positive predictive value) of gFOBTs when used to detect colorectal cancer (CRC) (with either repeated gFOBT testing or after a single [one-time] test)? 2. gFOBT Kit usability factors: What gFOBT kit factors affect acceptability by users? What is the effect of diet restrictions on gFOBT positivity? What is the effect of medication use on gFOBT positivity? 3. Laboratory factors: What laboratory protocols are required to maximize the accuracy of a gFOBT kit in terms of: Effect of temperature on specimen? Time interval between specimen collection and laboratory processing? Staff training? Definition of a positive screening test? Definition and resolution of an indeterminate result?"--Recommendations, page 1.