"Questions considered: 1. Does evaluation with bone scanning, liver ultrasonography, chest radiography, PET and PET-CT help to determine the extent of metastatic disease in women with newly diagnosed operable breast cancer who are otherwise asymptomatic? 2. In what stages of breast cancer is the prevalence of detectable metastatic disease high enough to justify routine testing with bone scanning, liver ultrasonography, chest radiography, PET, and PET-CT? 3. Is there a role for performing these tests before surgery or, for cases in which they are necessary, should they be performed only after surgery?"--Page iv.