While the research involves different populations, stakeholders, and settings, the results highlight the strength and diversity of knowledge translation in the province. [...] The initial partnership between the Alexis Nakota Sioux Nation and the University of Alberta was developed within this ethical space and was further guided by the Canadian Institutes of Health Research (CIHR) Guidelines for Health Research Involving Aboriginal People, and the principles of community-based participatory research.7,8 Results Members of the Alexis Nakota Sioux Nation and the Universi [...] Focus group participants noted the benefits and challenges of adapting and delivering the program and provided recommendations for improving both the content of the program and its delivery. [...] It is a proxy measure of community health and an important step toward self-determination.9 Capacity-building was an important part of the project and contributed to the success of the program adaptations, as did the community’s willingness to deliver the program as a part of the regular school curriculum.10 Community capacity was expanded through multiple project phases, including the opportunity [...] Culos-Reed and Lynette Stephenson, MSc), and covered topics from the broader exercise and cancer research literature, the emerging and quickly growing yoga and cancer research, and the medical oncology literature.