The purpose of this study was to describe how a federal government initiative fostered partnership development with business, labour, education, and provincial and territorial government in adult work-related literacy. Using a qualitative research case study design, the National Literacy Secretariat Business and Labour Partnership Program was examined during three periods of program development and change using three data sources. The findings describe the accomplishments and impacts of the program, definitions of partnerships, factors of a successful and unsuccessful partnership, and lessons learned. The results are discussed through three models of partnership development and program planning in adult education.