Clinical efficacy and cost of Allogenic Acellular Dermal Matrix (AADM) in implant-based breast reconstruction of post mastectomy cancer patients

Objective The purpose of this report is to carry out a systematic review of the use of AADM (brand names AlloDerm or DermaMatrix) for breast reconstruction following mastectomy with the objective of estimating the safety, health benefit and cost impact of this. [...] The objective of the study was to evaluate the impact of AlloDerm on the rate of tissue expansions. [...] Thus, use of AADM does not appear to result in any major reduction of the number of doctor’s office visits required to complete the expansion. [...] Rate of late complications and revision rates in the absence of AADM use The reported. [...] The estimated risk of complications and the risk of revisions due to specific complications reported in five large cohorts of breast reconstruction surgeries is reported.