She participated in the selection of included studies, data extraction, and design and execution of the literature search strategies; contributed to the environmental scan; wrote the draft; revised the report; and prepared the report for publication. [...] Kristen Moulton played a role in the selection of the included studies, assisted in data extraction, participated in the scanning of Cochrane and CADTH publications for inclusion of articles in languages other than English, contributed to the initial draft of the review, and provided comments and feedback regarding drafts. [...] Julie Polisena was involved in the study quality assessment and the tabulation and analysis of data and assisted in the writing of the report. [...] The Cochrane Handbook for Systematic Reviews of Interventions, which details the process of preparing Cochrane systematic reviews, defines a comprehensive search strategy as being replicable and thorough and as including a search of various sources.8 A comprehensive search strategy involves the development and implementation of a strategy that will lead to the identification of relevant published [...] The percentages of low-quality studies (Jadad score 0 to 2; 52% of English RCTs and 60% of RCTs that were reported in LOE) and high-quality studies (Jadad score 3 to 5; 48% of English RCTs and 40% of RCTs that were reported in LOE) were comparable (P = 0.23).