Infliximab and etanercept in patients with rheumatoid arthritis

Maria Judd was involved in the design of the project, literature screening, data abstraction and interpretation for the clinical review, and writing of the report. [...] Peter Tugwell was involved in the design of the project, review of trials, and analysis; and provided input on drafts and revisions of the report. [...] Objective The objective of this study is to provide a clinical review and economic evaluation relating to the introduction of infliximab and etanercept to the sequence of DMARDs used in the treatment of RA. [...] The Sharp score is the sum of two scores that evaluate the presence and severity of erosions and joint space narrowing on a scale of zero to three and zero to four for. [...] The results of the survey confirmed MTX as the primary choice in the treatment of aggressive RA.