Electronic Cigarettes for the Reduction or Cessation of Smoking

This disclaimer and any questions or matters of any nature arising from or relating to the content or use (or misuse) of this document will be governed by and interpreted in accordance with the laws of the Province of Ontario and the laws of Canada applicable therein, and all proceedings shall be subject to the exclusive jurisdiction of the courts of the Province of Ontario, Canada. [...] SUMMARY OF ABSTRACTS Electronic Cigarettes for the Reduction or Cessation of Smoking 2 Research Questions 1. What is the clinical evidence regarding the utility of electronic cigarettes for the reduction or cessation of smoking? [...] SUMMARY OF ABSTRACTS Electronic Cigarettes for the Reduction or Cessation of Smoking 4 1,10,15 The safety of e-cigarettes is also unknown, especially in the long term. [...] Table 2: Summary of Included Studies on Electronic Cigarettes for the Reduction or Cessation of Smoking or on Safety of Electronic Cigarettes First Author, Study Population(s), Outcome(s) Conclusion(s) Year Characteristics Intervention(s), Comparator(s) Health Technology Assessments 1 HIQA, 2017 HTA Adults and children Safety Most common side effects are Number of Placebo and nicotine [...] Reduction in quit rates with use of N = 14,122 ENNDS ENDS compared with no use of Smoking cessation ENDS aids Data is of low certainty and evidence is limited Hartmann-Boyce, SR & MA Current smokers Safety EC users more likely to abstain 3 2016 3 RCTs and 21 Placebo and non- Abstinence from from smoking than placebo EC cohort studies placebo EC smoking after at users, no di