This disclaimer and any questions or matters of any nature arising from or relating to the content or use (or misuse) of this document will be governed by and interpreted in accordance with the laws of the Province of Ontario and the laws of Canada applicable therein, and all proceedings shall be subject to the exclusive jurisdiction of the courts of the Province of Ontario, Canada. [...] An osseointegrated prosthesis (OIP) eliminates the problem interface between the socket prosthesis and the residual limb by attaching the prosthesis directly to the bone in the 7 residual limb. [...] With the abutment penetrating the skin, the wound is closed, allowing attachment of the external prosthesis to the intraosseous implant. [...] As the design of the OIP requires that the implant protrude through the skin to allow for direct connection to the prosthesis, there is potential for eventual bacterial colonization at the prosthesis-skin interface (stoma) and bacteria tracking up the 10 metal implant to the femur. [...] However, other issues could influence the reported outcomes, including the duration of use of a prosthesis pre-operatively, the length of the residual limb, and the prosthetic components (e.g., knees, feet) used 13 following OIP.