The current review seeks to determine the clinical effectiveness, safety, and cost-effectiveness of IRE for the treatment of patients with resectable and unresectable pancreatic or liver tumors. [...] Five of the included primary studies examined patients with pancreatic tumors.11-15 Three of the studies11-13 were prospective before and after studies without a control group and two of the studies were retrospective before and after studies without a control group.14,15 No relevant economic studies were identified. [...] Country of Origin Pancreatic Tumors Both of the systematic reviews that examined studies of patients with pancreatic cancer were conducted in the Netherlands.9,10 Two of the primary studies were conducted in Italy11,13 and three in the United States.12,14,15 Liver Tumors The systematic review that included studies of patients with liver cancer (along with studies in patients with pancreatic cancer [...] None of the included studies in the SRs used a design that included a comparator group, thus the results are only descriptive and not comparative.9,10 Additionally, Scheffer et al.9 considered most of the results of the included studies together, as opposed to separating the results based on the surgical approach, it was therefore difficult to determine whether the type of surgery (open, laparosco [...] Further detail regarding the clinical effectiveness and safety reported in the included studies is available in Appendix 4. What is the cost-effectiveness of irreversible electroporation (IRE) in patients with tumors of the pancreas or liver?
- Pages
- 30
- Published in
- Ottawa, Ontario
